Regulation of microRNAs
Given this pervasiveness and importance of miRNA-mediated gene regulation, it should come as little surprise that miRNAs themselves are also highly regulated. However, the recent explosion of knowledge on this topic has been remarkable, providing a primary motivation for publication of this book. As...
Saved in:
Other Authors / Creators: | Großhans, Helge. editor. |
---|---|
Other Corporate Authors / Creators: | SpringerLink (Online service) |
Format: | Electronic eBook |
Language: | English |
Edition: | 1st ed. 2010. |
Imprint: | New York, NY : Springer New York : Imprint: Springer, 2010. |
Series: | Advances in Experimental Medicine and Biology,
700 |
Subjects: | |
Online Access: | Available in Springer Biomedical and Life Sciences eBooks 2010 English/International. |
Summary: | Given this pervasiveness and importance of miRNA-mediated gene regulation, it should come as little surprise that miRNAs themselves are also highly regulated. However, the recent explosion of knowledge on this topic has been remarkable, providing a primary motivation for publication of this book. As miRNAs are transcribed by RNA polymerase II, the enzyme that also generates mRNAs, it was perhaps not unexpected that miRNA transcription would be subject to regulation, and we have willfully mitted this aspect from this monograph. However, what has been unexpected is the extent of post-transcriptional regulation of miRNAs that is illustrated in this book. Given this pervasiveness and importance of miRNA-mediated gene regulation, it should come as little surprise that miRNAs themselves are also highly regulated. However, the recent explosion of knowledge on this topic has been remarkable, providing a primary motivation for publication of this book. As miRNAs are transcribed by RNA polymerase II, the enzyme that also generates mRNAs, it was perhaps not unexpected that miRNA transcription would be subject to regulation, and we have willfully mitted this aspect from this monograph. However, what has been unexpected is the extent of post-transcriptional regulation of miRNAs that is illustrated in this book. |
---|---|
ISBN: | 9781441978233 (online) |
ISSN: | 2214-8019 ; |
Author Notes: |