Channelopathies in Heart Disease

This book provides an expert overview on ion channel-related arrhythmia mechanisms, and describes important advances in our understanding of how ion channel dysfunction causes cardiac disease. Both, scientific findings and clinical implications are presented and discussed by scientists who have cons...

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Bibliographic Details
Other Authors / Creators:Thomas, Dierk. editor.
Remme, Carol Ann. editor.
Other Corporate Authors / Creators:SpringerLink (Online service)
Format: Electronic eBook
Language:English
Edition:1st ed. 2018.
Imprint: Cham : Springer International Publishing : Imprint: Springer, 2018.
Series:Cardiac and Vascular Biology, 6
Subjects:
Online Access:Available in Springer Biomedical and Life Sciences eBooks 2018 English/International.
Table of Contents:
  • Introduction
  • Part 1: (Dys)function of cardiac ion channels. Cardiac sodium channel (dys)function and inherited arrhythmia syndromes
  • Potassium channels in the heart
  • Voltage-gated calcium channels and their roles in cardiac electrophysiology
  • HCN channels and cardiac pacemaking
  • Dysregulation of ionic homeostasis: relevance for cardiac arrhythmias
  • Part 2: Cardiac channelopathies: clinical and genetic findings. Long and short QT syndromes
  • Brugada syndrome: current perspectives
  • Sinus node disease and cardiac conduction disease
  • Catecholaminergic polymorphic ventricular tachycardia
  • Idiopathic ventricular fibrillation and early repolarization
  • Atrial fibrillation
  • Genetic testing for inheritable cardiac channelopathies
  • Part 3: Research into cardiac channelopathies: new avenues. Novel imaging techniques in cardiac ion channel research
  • Transgenic animal models of cardiac channelopathies – benefits and limitations
  • Induced pluripotent stem cell-derived cardiomyocytes: towards personalized therapeutic strategies?. .